Frequently asked questions

Straight answers. If something's missing, the methods page has the detail.

Does my data leave my computer?

No. The fitter runs entirely in your browser; your pasted measurements are never uploaded or stored on any server. The only optional outbound request is the “Compare to literature” feature, which sends a target identifier (never your data) to the public ChEMBL database. See the privacy note.

Is it accurate? How do I know I can trust the fit?

The built-in examples recover known published values — the α7 nicotinic receptor + acetylcholine curve recovers EC50 ≈ 132 µM and Hill ≈ 1.4, matching the literature. Beyond that, every fit reports 95% confidence intervals from a bootstrap, so you can see how well-determined each parameter actually is. The full method is documented on the methods page — nothing is hidden.

What about IC50 — does it handle inhibition curves?

Yes. The same 4PL engine fits decreasing (inhibition) curves; the recovered EC50 is simply your IC50. Load the “inhibition (IC50)” example in the fitter to see it.

Can I use the figures in a paper or report?

Yes. Export a clean, white-background chart as a 2× PNG (for slides and print) or as true vector SVG (for journals and editing). The confidence band, EC50 marker, and a stats inset are included, and the export matches what's on screen.

What models are supported?

Today, the four-parameter logistic (4PL) — the workhorse for dose-response and most receptor/enzyme assays. Three- and five-parameter variants and constrained fits are on the roadmap.

Is this useful for cannabis potency labs?

It's built with that niche in mind. Cannabinoid potency and dose-response assays are exactly the 4PL shape DoseFit fits, the units are configurable, and the in-browser, no-install workflow suits a busy lab bench. If you run a testing lab, we'd genuinely like your feedback on what reporting you need.

How is this different from GraphPad Prism?

Prism is powerful but expensive, desktop-bound, and needs installing and licensing. DoseFit is instant, in-browser, shareable, free for the core fitter, and adds a live “compare to literature” overlay Prism doesn't have. The paid tiers add saved methods, reporting, and audit/compliance features for labs.

Is it really free?

The fitter is free and stays free. Paid Pro and Compliance tiers add accounts, saved methods, compliant reporting, and audit trails for labs that need them.

What's coming next?

Comparing multiple curves on one plot, accounts with saved & versioned methods, branded PDF reports, and — for regulated labs — an audit trail, e-signatures, and a validated-method workflow.

Open the fitter →