Built for cell & gene therapy and biologics potency. Paste your curves → relative potency with a Fieller CI, equivalence-based parallelism (USP <1032>), 4PL fits with real covariance confidence intervals, and a Certificate of Analysis — no install, no upload, flat-rate.
Free to try · runs entirely in your browser · your data never leaves your machine
Live output: 4PL fit · 95% CI band · EC50 marker · published-potency overlay from ChEMBL.
Most fitters give you a number and a line. DoseFit gives you the number, how sure it is, and — for potency — relative potency and parallelism the way a regulator expects it. In the browser, flat-rate.
Joint common-shape fits, relative potency with a Fieller CI, and equivalence-based parallelism (USP <1032>/<1034>) — the modern method, not the over-sensitive F-test. Compare CAR-T constructs or lots the way a reviewer expects.
Parameter-covariance confidence intervals (Prism/R-standard, not optimistic), constrainable plateaus, and honest warnings when your EC50 is an extrapolation — with a residual-bootstrap cross-check.
One-click Certificate of Analysis (print to PDF) with results, QC verdict and method — plus publication-ready 2× PNG or vector SVG with the confidence band and EC50 marker.
Overlay the published potency distribution for a target (live from ChEMBL) and see exactly where your compound lands. And no install — it runs on any laptop or phone.
One dose, response per line — comma, space, or tab separated. Pick your dose unit.
10, 5 100, 38 1000, 93Get EC50 / IC50, Hill slope, plateaus and R² — each with a 95% confidence interval and a shaded band, computed right in the browser.
Pick a reference to get relative potency + parallelism, overlay the published range from ChEMBL, then download a CoA or a publication-ready PNG / SVG. Read the guide →
The fitter runs entirely in your browser — your measurements are never uploaded, stored, or sent to any server. The only optional network request is the “Compare to literature” feature, which fetches public reference data by target (never your data). For a lab handling sensitive results, that’s the point. Read the privacy note →
The fitter is free, forever. Paid tiers add accounts, saved methods, and compliant reporting as your lab needs them.
The full browser tool.
For working scientists.
For regulated labs.
No sign-up. Load an example or paste your own data.